Selective Alkylation and Acylation of α and ε Amino Groups with PEG in a Somatostatin Analogue: Tailored Chemistry for Optimized Bioconjugates
- 29 October 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Bioconjugate Chemistry
- Vol. 13 (6), 1238-1243
- https://doi.org/10.1021/bc0100511
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Peptide and protein PEGylation: a review of problems and solutionsBiomaterials, 2001
- Early Administration of Vapreotide for Variceal Bleeding in Patients with CirrhosisThe New England Journal of Medicine, 2001
- Poly(ethylene glycol) Conjugated Drugs and Prodrugs: A Comprehensive ReviewCritical Reviews in Therapeutic Drug Carrier Systems, 2000
- Site-specific insulin conjugates with enhanced stability and extended action profileAdvanced Drug Delivery Reviews, 1999
- Development and evaluation in vivo of a long-term delivery system for vapreotide, a somatostatin analogueJournal of Controlled Release, 1998
- Branched and Linear Poly(Ethylene Glycol): Influence of the Polymer Structure on Enzymological, Pharmacokinetic, and Immunological Properties of Protein ConjugatesJournal of Bioactive and Compatible Polymers, 1997
- Improvement of pharmacokinetic, immunological and stability properties of asparaginase by conjugation to linear and branched monomethoxy poly( ethylene glycol)Journal of Controlled Release, 1996
- The therapeutic value of poly(ethylene glycol)-modified proteinsAdvanced Drug Delivery Reviews, 1991
- Rapid analysis of amino acids using pre-column derivatizationJournal of Chromatography B: Biomedical Sciences and Applications, 1984