Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy
- 17 April 2013
- journal article
- review article
- Published by Elsevier BV in Trends in Parasitology
- Vol. 29 (5), 207-212
- https://doi.org/10.1016/j.pt.2013.03.004
Abstract
No abstract availableKeywords
Funding Information
- Medical Research Council (MR/K000500/1, MR/K008749/1, MR/K011987/1, 082813, 093010/Z/10/Z)
- Wellcome Trust (MR/K000500/1, MR/K008749/1, MR/K011987/1, 082813, 093010/Z/10/Z)
This publication has 60 references indexed in Scilit:
- High-throughput decoding of antitrypanosomal drug efficacy and resistanceNature, 2012
- The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine SiteJournal of Biological Chemistry, 2011
- The VSG C-terminal domain is inaccessible to antibodies on live trypanosomesMolecular and Biochemical Parasitology, 2011
- Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6Molecular and Biochemical Parasitology, 2010
- Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factorProceedings of the National Academy of Sciences of the United States of America, 2010
- A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal traffickingNature Structural & Molecular Biology, 2010
- N-myristoyltransferase inhibitors as new leads to treat sleeping sicknessNature, 2010
- Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trialThe Lancet, 2009
- Targeted therapies in breast cancer: Where are we now?European Journal Of Cancer, 2008
- Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serumProceedings of the National Academy of Sciences of the United States of America, 2007