Aqueous toxicity and food chain transfer of quantum dots™ in freshwater algae and Ceriodaphnia dubia
- 1 September 2008
- journal article
- nanomaterials in-the-environment
- Published by Wiley in Environmental Toxicology and Chemistry
- Vol. 27 (9), 1958-1963
- https://doi.org/10.1897/07-637.1
Abstract
Innovative research and diagnostic techniques for biological testing have advanced during recent years because of the development of semiconductor nanocrystals. Although these commercially available, fluorescent nanocrystals have a protective organic coating, the inner core contains cadmium and selenium. Because these metals have the potential for detrimental environmental effects, concerns have been raised over our lack of understanding about the environmental fate of these products. U.S. Environmental Protection Agency test protocol and fluorescence microscopy were used to determine the fate and effect of quantum dots (QDs; Qdot® 545 ITK™ Carboxyl Quantum Dots [Fisher Scientific, Fisher part Q21391MP; Invitrogen Molecular Probes, Eugene, OR, USA]) using standard aquatic test organisms. No lethality was measured following 48‐h exposure of Ceriodaphnia dubia to QD suspensions as high as 110 ppb, but the 96‐h median lethal concentration to Pseudokirchneriella subcapitata was measured at 37.1 ppb. Transfer of QDs from dosed algae to C. dubia was verified with fluorescence microscopy. These results indicate that coatings present on nanocrystals provide protection from metal toxicity during laboratory exposures but that the transfer of core metals from intact nanocrystals may occur at levels well above toxic threshold values, indicating the potential exposure of higher trophic levels. Studies regarding the fate and effects of nanoparticles can be incorporated into models for predictive toxicology of these emerging contaminants.Keywords
This publication has 30 references indexed in Scilit:
- Chlamydomonas pitschmannii Ettl, a Little Known Species from Thermoacidic EnvironmentsProtist, 2005
- Manufactured Nanomaterials (Fullerenes, C 60 ) Induce Oxidative Stress in the Brain of Juvenile Largemouth BassEnvironmental Health Perspectives, 2004
- Quantum dot-based cell motility assayDifferentiation, 2003
- The potential environmental impact of engineered nanomaterialsNature Biotechnology, 2003
- Surface binding of contaminants by algae: Consequences for lethal toxicity and feeding to Daphnia magna strausEnvironmental Toxicology and Chemistry, 1998
- Influence of exposure time on the distribution of cadmium within the cladoceran Ceriodaphnia dubiaAquatic Toxicology, 1998
- Short‐term toxicity test based on algal uptake by Ceriodaphnia dubiaWater Environment Research, 1997
- Ceriofast™: An acute toxicity test based onCeriodaphnia dubiafeeding behaviorEnvironmental Toxicology and Chemistry, 1996
- Morphological and ultrastructural effects of sublethal cadmium poisoning on DaphniaEnvironmental Research, 1980
- Effects of copper, zinc and cadmium on Selanastrum CapricornutumWater Research, 1974