A mechanism for eye position effects on spontaneous nystagmus
- 1 August 2012
- conference paper
- Published by Institute of Electrical and Electronics Engineers (IEEE) in 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
- Vol. 2012 (1094687X), 3572-3575
- https://doi.org/10.1109/embc.2012.6346738
Abstract
In acute stages of unilateral vestibular deficit, the imbalanced tonic activity on vestibular afferents evokes spontaneous nystagmus. The slow-phase velocity of this nystagmus varies with eye position, such that it is smaller when looking in the direction of slow-phases. The neural mechanism for this behavior is still not understood. Here, using a simple control system model, we show that plausible changes in the neural responses within the central vestibulo-ocular reflex pathway are adequate to cause eye position dependent effects in the nystagmus pattern. The proposed transformations in population response functions could happen immediately following a lesion and can be useful to stabilize gaze in part of the gaze field.Keywords
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