SPECIFICITY OF FIBRONECTIN‐FIBRIN CROSS‐LINKING*
- 1 June 1983
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 408 (1), 583-594
- https://doi.org/10.1111/j.1749-6632.1983.tb23275.x
Abstract
Our experiments indicate that (1) non-covalent binding of fibronectin to fibrin is mediated by sites in a 27 kd NH2-terminal region and a 31 kd COOH-terminal region of fibronectin; (2) the 31 kd region is probably present in both chains of the fibronectin dimer; and (3) covalent (factor XIIIa-mediated) cross-linking of fibronectin and fibrin is between a glutaminyl residue in the 27 kd region of fibronectin and a lysyl residue in the COOH-terminal two-thirds of the fibrin alpha chain.Keywords
This publication has 23 references indexed in Scilit:
- Amino acid sequence of the factor XIIIa acceptor site in bovine plasma fibronectinFEBS Letters, 1981
- Location of Heparin-Binding Sites of Fibronectin. Detection of a hitherto Unrecognized Transamidase Sensitive SiteHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1981
- Identification of two fibrin-binding domains in plasma fibronectin and unequal distribution of these domains in two different subunits: A preliminary noteBiochemical and Biophysical Research Communications, 1980
- Binding and Factor XIII a -Mediated Cross-Linking of a 27-Kilodalton Fragment of Fibronectin to Staphylococcus aureusScience, 1980
- Fibroblast adhesion to fibrinogen and fibrin substrata: Requirement for cold-insoluble globulin (plasma fibronectin)Cell, 1980
- Fibronectin, VII. Binding of Cold-Insoluble Globulin and of Denatured Collagen by MacrophagesHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1980
- Cross-linking of fibronectin to collagen by blood coagulation Factor XIIIa.JCI Insight, 1979
- Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences of the United States of America, 1979
- Inhibition of blood coagulation factor XIIIa‐mediated cross‐linking between fibronectin and collagen by polyaminesJournal of Supramolecular Structure, 1979
- The formation of crosslinked fibrins: Evidence for the involvement of lysine ε-amino groupsBiochemical and Biophysical Research Communications, 1966