Premedication for Peroral Endoscopy two Double-Blind Studies
- 1 January 1972
- journal article
- clinical trial
- Published by Informa UK Limited in Scandinavian Journal of Gastroenterology
- Vol. 7 (7), 583-587
- https://doi.org/10.3109/00365527209180960
Abstract
The effect of an intramuscular injection of 10 mg of diazepam and of a subcutaneous injection of 2 mg of hydromorphone hydrochloride plus 0.3 mg. of atropine in the premedication for peroral endoscopy was compared with physiological saline in double-blind trials. Only flexible fiberscopes were used. Three-fourths of the 46 patients who received physiological saline alone appeared to be satisfactorily premedicated. Diazepam showed no significant effects, but hydromorphone-atropine showed significant beneficial effects on anxiety, salivation, vomiting, and discomfort.Keywords
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