COVID-19 vaccine race: watch your step for cancer patients
Open Access
- 2 March 2021
- journal article
- editorial
- Published by Springer Science and Business Media LLC in British Journal of Cancer
- Vol. 124 (5), 860-861
- https://doi.org/10.1038/s41416-020-01219-3
Abstract
Patients with cancer should benefit from COVID-19 vaccination. Some of the most advanced vaccine candidates are mRNAs encapsulated into lipid carriers, and small liposomes are expected to accumulate in tumour tissues through the enhanced and permeation retention effect. However, to what extent solid tumours could take up a significant part of the vaccine dose as well remains unknown. This calls for a careful evaluation of the efficacy of these promising mRNA COVID-19 vaccines administered as lipid carriers for patients with solid tumours, including a possible re-appraisal of the dosing for optimal protection of this specific and frail population.This publication has 12 references indexed in Scilit:
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