High-yield production of citric acid by Yarrowia lipolytica on glycerol in repeated-batch bioreactors
- 3 January 2010
- journal article
- Published by Oxford University Press (OUP) in Journal of Industrial Microbiology & Biotechnology
- Vol. 37 (5), 431-435
- https://doi.org/10.1007/s10295-009-0687-8
Abstract
An acetate negative mutant of Yarrowia lipolytica Wratislavia AWG7 was found to be suitable for the production of high amounts of citric acid in long-term repeated-batch cultures. When 40% of fresh replaced medium was fed, this strain produced 154 g l−1, on average, which corresponded to a 0.78 g g−1 yield and a productivity of 1.05 g l−1 h−1. The activity of the culture remained stable for more than 1,650 h, i.e., 16 cycles of the repeated-batch bioreactors.Keywords
This publication has 16 references indexed in Scilit:
- Citric Acid Production Patent ReviewRecent Patents on Biotechnology, 2008
- Characterization of Yarrowia lipolytica and related species for citric acid production from glycerolEnzyme and Microbial Technology, 2007
- Citric acid production from sucrose using a recombinant strain of the yeast Yarrowia lipolyticaApplied Microbiology and Biotechnology, 2007
- Optimization of medium constituents for the production of citric acid from byproduct glycerol using Doehlert experimental designEnzyme and Microbial Technology, 2007
- Citric acid production from glucose by yeast Candida oleophila ATCC 20177 under batch, continuous and repeated batch cultivationElectronic Journal of Biotechnology, 2006
- Organic Acid Production by the Yeast Yarrowia lipolytica: A Review of ProspectsApplied Biochemistry and Microbiology, 2005
- Optimization of citric acid production from Candida lipolytica Y-1095 using n-paraffinJournal of Biotechnology, 2001
- Biosynthesis of citric acid by Yarrowia lipolytica repeat-batch culture on ethanolApplied Microbiology and Biotechnology, 2000
- Effect of glucose concentration on citric acid production by Yarrowia lipolyticaJournal of Chemical Technology & Biotechnology, 1994
- Itaconic acid production from xylose in repeated-batch and continuous bioreactorsApplied Microbiology and Biotechnology, 1990