Three cases of antibody-LGI1 limbic encephalitis and review of literature
- 6 February 2019
- journal article
- review article
- Published by Taylor & Francis Ltd in International Journal of Neuroscience
- Vol. 129 (7), 642-648
- https://doi.org/10.1080/00207454.2018.1512985
Abstract
Antibody-LGI1 limbic encephalitis(LGI1-Ab LE) is an anti-neuronal surface antigen related autoimmune encephalitis, which clinically manifests through memory impairment, faciobrachial dystonic seizures (FBDS), epileptic seizures, behavior disorders, and hyponatremia. Now, we reported three cases of LGI1-Ab LE. The clinical features of our patients presented with memory impairment, epileptic seizures, hyponatremia, and two patients presented with behavior disorders. All serum LGI1 antibodies were positive, whereas one patient LGI1 antibodies of cerebrospinal fluid (CSF) was negative. Gammaglobulin, hormone or both in combination were administered to them, the clinical symptoms improved significantly.This publication has 22 references indexed in Scilit:
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