Mechanism and Therapeutic Reversal of Immune Suppression in Cancer

Abstract
The meeting began with a discussion of the historical perspective of cancer immunotherapy from bench to bedside ( 1). The concept of “checkpoint blockades” was described as the body's attempt at preventing autoimmunity and thereby thwarting attempts at harnessing the immune system in the eradication of cancer. [Cancer Res 2007;67(11):5067–9]