Articular cartilage preservation and storage

Abstract

Mature rabbit articular cartilage in the form of distal femoral condyles, composite osteoarticular structures, were incubated in the presence of α‐tocopherol (200 μg/ml) over a period of time. Indentation testing and ³⁵S uptake indicate preservation of sustained load carrying capacity and viability, respectively, in the presence of α‐tocopherol for up to 30 days in organ culture. Condylar cartilage stored in the absence of α‐tocopherol as well as frozen cartilage demonstrated progressive inability to resist sustained loading over time. Nonoptimal synthetic function apparently occurred in these latter two groups when compared to α‐tocopherol stored material.