On the Residence Time for Water in a Solute Hydration Shell: Application to Aqueous Halide Solutions
- 30 May 2008
- journal article
- Published by American Chemical Society (ACS) in The Journal of Physical Chemistry B
- Vol. 112 (26), 7697-7701
- https://doi.org/10.1021/jp802033r
Abstract
We investigate several different methods to determine the water residence time next to a solute from molecular dynamics simulations. The popular computational prescription due to Impey et al. ( J. Phys. Chem. 1983, 87, 5071-5083) is shown to be extremely sensitive to the t* tolerance time value (designed to account for barrier recrossing effects), and we evidence through a kinetic analysis that the conventionally employed t* = 2 ps value can yield seriously overestimated residence times for low barrier exchanges. We suggest an alternate, robust determination based on the stable states picture (SSP) of chemical reactions ( J. Chem. Phys. 1980, 73, 2700-2714) where recrossing is naturally discarded. This is illustrated by calculation of the water residence time next to a water molecule and next to a chloride ion, using both nonpolarizable and polarizable force-fields. The SSP results are in good agreement with the residence times estimated by a separate kinetic analysis, and differ noticeably from those calculated in the conventional fashion mentioned above.Keywords
This publication has 36 references indexed in Scilit:
- How Protein Surfaces Induce Anomalous Dynamics of Hydration WaterThe Journal of Physical Chemistry B, 2007
- Coordination and ligand exchange dynamics of solvated metal ionsCoordination Chemistry Reviews, 2005
- Hydration Layer of a Cationic Micelle, C10TAB: Structure, Rigidity, Slow Reorientation, Hydrogen Bond Lifetime, and Solvation DynamicsThe Journal of Physical Chemistry B, 2005
- Dynamics of Protein and Peptide HydrationJournal of the American Chemical Society, 2003
- Molecular Dynamics of Water at the Protein−Solvent InterfaceThe Journal of Physical Chemistry B, 2002
- Residence Times of Water Molecules in the Hydration Sites of MyoglobinBiophysical Journal, 2000
- Solvent Structure, Dynamics, and Ion Mobility in Aqueous Solutions at 25 °CThe Journal of Physical Chemistry B, 1998
- Hydration in protein crystallographyProgress in Biophysics and Molecular Biology, 1995
- Hydration of ProteinsJournal of Molecular Biology, 1993
- Experimental determination of the nature of diffusive motions of water molecules at low temperaturesPhysical Review A, 1985