Fragment screening: an introduction
- 2 August 2006
- journal article
- book charpter
- Published by Royal Society of Chemistry (RSC) in Molecular BioSystems
- Vol. 2 (9), 429-446
- https://doi.org/10.1039/b610069b
Abstract
A graphical abstract is available for this contentKeywords
This publication has 47 references indexed in Scilit:
- Design and Characterization of Libraries of Molecular Fragments for Use in NMR Screening against Protein TargetsJournal of Chemical Information and Computer Sciences, 2004
- A ‘Rule of Three’ for fragment-based lead discovery?Drug Discovery Today, 2003
- Cheminformatics Analysis of Organic Substituents: Identification of the Most Common Substituents, Calculation of Substituent Properties, and Automatic Identification of Drug-like Bioisosteric GroupsJournal of Chemical Information and Computer Sciences, 2002
- Molecular Complexity and Its Impact on the Probability of Finding Leads for Drug DiscoveryJournal of Chemical Information and Computer Sciences, 2001
- Where Are the GaPs? A Rational Approach to Monomer Acquisition and SelectionJournal of Chemical Information and Computer Sciences, 2000
- The Design of Leadlike Combinatorial LibrariesAngewandte Chemie, 1999
- ChemInform Abstract: RECAP — Retrosynthetic Combinatorial Analysis Procedure: A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry.ChemInform, 1998
- RECAPRetrosynthetic Combinatorial Analysis Procedure: A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial ChemistryJournal of Chemical Information and Computer Sciences, 1998
- X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human α-thrombinFEBS Letters, 1998
- The Properties of Known Drugs. 1. Molecular FrameworksJournal of Medicinal Chemistry, 1996