A Theoretical Study of the Steady-State Model for Measuring Regional Cerebral Blood Flow and Oxygen Utilisation Using Oxygen-15

Abstract

There is a growing interest in the tomographic measurement of regional cerebral blood flow and oxygen utilisation using continuous inhalation of C¹⁵O₂ and ¹⁵O₂. This paper examines the influence of certain assumptions in the underlying steady-state model. Estimations are made for possible errors in the actual measurement of these quantities in grey and white matter.