Effect of bronchodilation on expiratory flow limitation and resting lung mechanics in COPD

Abstract

Bronchodilator drugs produce variable improvements in forced expiratory volume in 1 s (FEV₁), but larger changes in end-expiratory lung volume (EELV) in chronic obstructive pulmonary disease (COPD), which were suggested to be related to the presence of expiratory flow limitation (EFL) at rest.