ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents
Open Access
- 1 February 2004
- journal article
- review article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 89 (2), 188-194
- https://doi.org/10.1136/adc.2003.044875
Abstract
Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus (TIDM). Mortality is predominantly related to the occurrence of cerebral oedema; only a minority of deaths in DKA are attributed to other causes. Cerebral oedema occurs in about 0.3–1% of all episodes of DKA, and its aetiology, pathophysiology, and ideal method of treatment are poorly understood. There is debate as to whether physicians treating DKA can prevent or predict the occurrence of cerebral oedema, and the appropriate site(s) for children with DKA to be managed. There is agreement that prevention of DKA and reduction of its incidence should be a goal in managing children with diabetes.Keywords
This publication has 92 references indexed in Scilit:
- Maintaining normal intracranial pressure in a rabbit model during treatment of severe diabetic ketoacidemiaLife Sciences, 1996
- Minimizing the risk of brain herniation during treatment of diabetic ketoacidemia: A retrospective and prospective studyThe Journal of Pediatrics, 1990
- Adult respiratory distress syndrome in an adolescent with diabetic ketoacidosisThe Journal of Pediatrics, 1987
- Isolated Growth Hormone Deficiency after Cerebral Edema Complicating Diabetic KetoacidosisNew England Journal of Medicine, 1987
- An approach to prevention of recurrent diabetic ketoacidosis in the pediatric populationThe Journal of Pediatrics, 1985
- Subclinical Brain Swelling in Children during Treatment of Diabetic KetoacidosisNew England Journal of Medicine, 1985
- Plasma free insulin concentrations: Keystone toeffective management of diabetes mellitus in childrenThe Journal of Pediatrics, 1981
- Cerebral hypoxia from bicarbonate infusion in diabetic acidosisThe Journal of Pediatrics, 1980
- Low-dose insulin infusion in the treatment of diabetic ketoacidosis: Bolus versus no bolusThe Journal of Pediatrics, 1980
- Retention of water and electrolyte during recovery in a patient with diabetic acidosisThe Journal of Pediatrics, 1952