Idiopathic Lenticular Mucocutaneous Pigmentation or Laugier-Hunziker Syndrome With Atypical Features

Abstract

Laugier-Hunziker syndrome is a rare, acquired pigmentary disorder of the lips, oral mucosa, and nails. In 1970, Laugier and Hunziker¹ reported on 5 cases of essential melanotic pigmentation of the mouth and lips. Two of these patients also displayed pigmentary changes of the nails. In the meantime, several authors,² particularly from western Europe, presented more patients with this syndrome. Recently, we examined a patient with mucocutaneous features of both Laugier-Hunziker and Peutz-Jeghers syndrome, whose family history was negative, and in whom, on repeated examinations, intestinal polyposis was not detectable. Report of a Case. A 50-year-old white man first presented at our outpatient clinic in 1982 with a 12-year history of asymptomatic melanotic macules on his lips, oral mucosa, and several fingers. Apart from a noninsulin-dependent diabetes mellitus and coronary heart disease, which had been treated with glibenclamid and sotalol since 1981, his personal history was unremarkable. There was