Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids
- 1 November 1981
- journal article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 294 (5838), 228-232
- https://doi.org/10.1038/294228a0
Abstract
Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome.This publication has 21 references indexed in Scilit:
- Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.Molecular and Cellular Biology, 1981
- Equilibrium: the intracellular distribution of steroid receptorsNature, 1979
- Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.Proceedings of the National Academy of Sciences of the United States of America, 1979
- Molecular Mechanisms of Steroid Hormone ActionAdvances in Cancer Research, 1978
- Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.Proceedings of the National Academy of Sciences of the United States of America, 1977
- Steroid Receptors: Elements for Modulation of Eukaryotic TranscriptionAnnual Review of Biochemistry, 1976
- Current models of steroid hormone action: a critique.Annual Review of Physiology, 1976
- Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid actionCell, 1975
- Receptors from Glucocorticoid-Sensitive Lymphoma Cells and Two Classes of Insensitive Clones: Physical and DNA-Binding PropertiesProceedings of the National Academy of Sciences of the United States of America, 1974
- A two-step mechanism for the interaction of estradiol with rat uterus.Proceedings of the National Academy of Sciences of the United States of America, 1968