Lymphocytotoxins in rheumatoid arthritis: prevalence, lymphocyte specificity, and HLA-DR antigens.
Open Access
- 1 April 1981
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 40 (2), 154-156
- https://doi.org/10.1136/ard.40.2.154
Abstract
37% (57/155) of sera from patients with rheumatoid arthritis contain cold-reacting lymphocytotoxic antibodies. Lymphocytotoxins were predominantly of the weakly reactive type and were more likely to be present in patients who were HLA-DR4 positive. By contrast, patients who were HLA-DR3 positive were more likely to have strongly reactive lymphocytotoxins. The lymphocyte subclass reactivity of the lymphocytotoxins was: 67% versus B lymphocytes, 27% against both T and B cells, and 7% for T cells.This publication has 11 references indexed in Scilit:
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