The role of sunlight exposure in determining the vitamin D status of the U.K. white adult population
- 12 August 2010
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 163 (5), 1050-1055
- https://doi.org/10.1111/j.1365-2133.2010.09975.x
Abstract
Background Vitamin D is necessary for bone health and is potentially protective against a range of malignancies. Opinions are divided on whether the proposed optimal circulating 25-hydroxyvitamin D [25(OH)D] level (≥ 32 ng mL−1) is an appropriate and feasible target at population level. Objectives We examined whether personal sunlight exposure levels can provide vitamin D sufficient (≥ 20 ng mL−1) and optimal status in the U.K. public. Methods This prospective cohort study measured circulating 25(OH)D monthly for 12 months in 125 white adults aged 20–60 years in Greater Manchester. Dietary vitamin D and personal ultraviolet radiation (UVR) exposure were assessed over 1–2 weeks in each season. The primary analysis determined the post-summer peak 25(OH)D required to maintain sufficiency in wintertime. Results Dietary vitamin D remained low in all seasons (median 3·27 μg daily, range 2·76–4·15) while personal UVR exposure levels were high in spring and summer, low in autumn and negligible in winter. Mean 25(OH)D levels were highest in September [28·4 ng mL−1; 28% optimal, zero deficient (−1)], and lowest in February (18·3 ng mL−1; 7% optimal, 5% deficient). A February 25(OH)D level of 20 ng mL−1 was achieved following a mean (95% confidence interval) late summer level of 30·4 (25·6–35·2) and 34·9 (27·9–41·9) ng mL−1 in women and men, respectively, with 62% of variance explained by gender and September levels. Conclusions Late summer 25(OH)D levels approximating the optimal range are required to retain sufficiency throughout the U.K. winter. Currently the majority of the population fails to reach this post-summer level and becomes vitamin D insufficient during the winter.This publication has 22 references indexed in Scilit:
- Vitamin D Status: Measurement, Interpretation, and Clinical ApplicationAnnals of Epidemiology, 2009
- Molecular basis of the potential of vitamin D to prevent cancerCurrent Medical Research and Opinion, 2008
- Vitamin D: Its role in cancer prevention and treatmentProgress in Biophysics and Molecular Biology, 2006
- The vitamin D questions: How much do you need and how should you get it?Journal of the American Academy of Dermatology, 2006
- Calculated Ultraviolet Exposure Levels for a Healthy Vitamin D StatusPhotochemistry and Photobiology, 2006
- Circulating 25-Hydroxyvitamin D Levels Indicative of Vitamin D Sufficiency: Implications for Establishing a New Effective Dietary Intake Recommendation for Vitamin DJournal of Nutrition, 2005
- Vitamin D in preventive medicine: are we ignoring the evidence?British Journal of Nutrition, 2003
- Vitamin D Metabolism, Rickets, and OsteomalaciaSeminars in Musculoskeletal Radiology, 2002
- The standard erythema dose: a new photobiological conceptPhotodermatology, Photoimmunology & Photomedicine, 1997
- The Role of Sunlight in the Cutaneous Production of Vitamin D3Annual Review of Nutrition, 1988