Abstract
A received criticism of information is that it is an instrumentalization of knowledge. This article questions the conditions for such a critique. Examining developmental systems theory, biology and social sciences, it argues that information is a situated event; that it is intrinsic to the development and (de)structuring of mnemic organization (meaning) at a number of levels; and that such developmental systems are epigenetically constituted. This concept of information leads to: a critique of the statistical-quantitative determination of information that is put forward as its mathematical theorization; a review of characterizations of ‘information societies’; and comprehending instrumentalization as a variant of the event of information at the specific level of the constitution of the human understood as an anthropotechnical complex.

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