Postprandial glycaemic and insulinaemic responses to GM-resistant starch-enriched rice and the production of fermentation-related H2in healthy Chinese adults
- 24 November 2009
- journal article
- clinical trial
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 103 (7), 1029-1034
- https://doi.org/10.1017/s0007114509992820
Abstract
Consumption of resistant starch (RS)-enriched foods is associated with decrease in the postprandial glycaemic and insulinaemic responses, accompanied by the production of fermentation-related gases in the large bowel. The present study aimed to determine the postprandial glycaemic and insulinaemic responses to the GM RS-enriched rice and the fermentation-related production of H2 in young and healthy Chinese adults. A total of sixteen young adults (nine men and seven women) were recruited and divided into three groups. Their postprandial glycaemic and insulinaemic responses to 40 g glucose, carbohydrates of RS or wild-type (WT) rice were tested by a crossover model with a washout period of 7 d. The concentrations of blood glucose and insulin as well as breath H2 were measured before and after food intake. Although the mean concentrations of fasting blood glucose, insulin and breath H2 were similar, consumption of the RS rice significantly decreased the values of glycaemic index (GI) and insulin index (II), as compared with the intake of WT rice (48·4 (sem 21·8) v. 77·4 (sem 34·9) for GI, 34·2 (sem 18·9) v. 54·4 (sem 22·4) for II, P < 0·05), respectively. Conversely, intake of the RS rice meal significantly elevated the concentrations of breath H2, as compared with WT rice (38·9 (sem 17·6) v. 10·5 (sem 3·7) parts per million for peak levels of breath H2, P < 0·05) through a period of 16-h tests. Consumption of the GM RS-enriched rice meal decreased the postprandial glycaemic and insulinaemic responses and promoted RS fermentation-related production of H2 in the large bowel of young and healthy Chinese adults.Keywords
This publication has 34 references indexed in Scilit:
- Resistant starch for weaning pigs — Effect on concentration of short chain fatty acids in digesta and intestinal morphologyLivestock Science, 2007
- In vitro measurement of resistant starch of cooked milled rice and physico-chemical characteristics affecting its formationFood Chemistry, 2007
- Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in ratsCarcinogenesis: Integrative Cancer Research, 2006
- Consumption of Both Resistant Starch and β-Glucan Improves Postprandial Plasma Glucose and Insulin in WomenDiabetes Care, 2006
- Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?Carcinogenesis: Integrative Cancer Research, 2005
- Topical butyrate improves efficacy of 5‐ASA in refractory distal ulcerative colitis: results of a multicentre trialEuropean Journal of Clinical Investigation, 2003
- Resistant starch and “the butyrate revolution”Trends in Food Science & Technology, 2002
- The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years.Diabetes Care, 1999
- The control and consequences of bacterial fermentation in the human colonJournal of Applied Bacteriology, 1991
- Use of pulmonary hydrogen (H2) measurements to quantitate carbohydrate absorptionJCI Insight, 1972