Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection
Open Access
- 17 September 2012
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 209 (10), 1769-1779
- https://doi.org/10.1084/jem.20120905
Abstract
Autoimmunity occurs because central and peripheral tolerance mechanisms fail to tolerize T cells with weak self-reactivity to tissue-restricted antigen.Keywords
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