Unipolar depression does not moderate responses to the Sweet Taste Test
- 30 August 2010
- journal article
- research article
- Published by Hindawi Limited in Depression and Anxiety
- Vol. 27 (9), 859-863
- https://doi.org/10.1002/da.20690
Abstract
Background: The Sweet Taste Test (STT) measures hedonic responses to sweet tastes and has been linked to both alcoholism and to a family history of alcoholism. However, STT response profiles in unipolar major depressive disorder (MDD), a disorder characterized by anhedonia, have been minimally investigated. Methods: Twelve adults with and 15 adults without MDD participated in two identical STT assessments separated by approximately 12 weeks. Between assessments, MDD outpatients received Behavioral Activation Therapy for Depression, a psychotherapy modality designed to increase engagement with rewarding stimuli and reduce avoidance behaviors. Primary‐dependent measures included sensitivity to sucrose, hedonic response to sucrose, and designation as a Sweet‐Liker or Sweet‐Disliker. Results: A total of 75% of adults with MDD were treatment responders. There were no significant differences in STT response profiles between groups overall or at either timepoint. Furthermore, STT profiles of MDD participants did not differ after psychotherapy, relative to baseline. Conclusions: Findings suggest that although anhedonia is a symptom of MDD, the disorder is not characterized by altered responses to sweet tastes. Implications and future directions are discussed. Depression and Anxiety, 2010.This publication has 37 references indexed in Scilit:
- fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorderJournal of Affective Disorders, 2009
- The Effects of Psychotherapy on Neural Responses to Rewards in Major DepressionBiological Psychiatry, 2009
- Sweet Liking Phenotype, Alcohol Craving and Response to Naltrexone Treatment in Alcohol DependenceAlcohol and Alcoholism, 2009
- Altered Striatal Activation Predicting Real-World Positive Affect in Adolescent Major Depressive DisorderAmerican Journal of Psychiatry, 2009
- Neural Responses to Monetary Incentives in Major DepressionBiological Psychiatry, 2008
- Affective neuroscience of pleasure: reward in humans and animalsPsychopharmacology, 2008
- The chronometry of affective startle modulation in unipolar depression.Journal of Abnormal Psychology, 2008
- Qualitative Descriptors of Strength of Association and Effect SizeJournal of Social Service Research, 1996
- Predicting premorbid IQ: A revision of the national adult reading testThe Clinical Neuropsychologist, 1989
- A comparison of the Two One-Sided Tests Procedure and the Power Approach for assessing the equivalence of average bioavailabilityJournal of Pharmacokinetics and Biopharmaceutics, 1987