Stable and Functionable Mesoporous Silica-Coated Gold Nanorods as Sensitive Localized Surface Plasmon Resonance (LSPR) Nanosensors
- 17 August 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in Langmuir
- Vol. 25 (16), 9441-9446
- https://doi.org/10.1021/la900646n
Abstract
Core-shell structured Au NRs with a surface-exposed gold core and a mesoporous silica shell (MS Au NRs) were demonstrated as a promising platform for localized surface plasmon resonance (LSPR) based molecular sensing. Mesoporous silica shell not only allows the Au NRs core to be directly exposed to their surrounding environment but also stabilizes Au NRs dispersion in various water-organic mixtures and pure organic solvents. The LSPR band of MS Au NRS displays a stable and linear response in spectral shift to the changes in their Surrounding refractive index with a sensitivity of 325 nm/RIU. To demonstrate the application of MS Au NRs as LSPR nanosensors in molecular sensing, the plasmon response to molecular adsorbates (GSH) was demonstrated. MS Au NRs provide a more stable and sensitive response than CTAB-capped An NRs in GSH sensing. In addition, we have also demonstrated that the LSPR response of Au NRs is highly sensitive to changes of local refractive index in mesoporous silica shell, which renders the feasibility of using MS Au NRs as effective molecule-sensing platforms when mesoporous silica shells were functionalized with various chemical and biological ligands.This publication has 37 references indexed in Scilit:
- Optical extinction spectrum of a single metal nanoparticle: Quantitative characterization of a particle and of its local environmentPhysical Review B, 2008
- Direct observation of chemical reactions on single gold nanocrystals using surface plasmon spectroscopyNature Nanotechnology, 2008
- Biosensing with plasmonic nanosensorsNature Materials, 2008
- Protein–Membrane Interaction Probed by Single Plasmonic NanoparticlesNano Letters, 2008
- A Calcium-Modulated Plasmonic SwitchJournal of the American Chemical Society, 2008
- Localized Surface Plasmon Resonance Spectroscopy and SensingAnnual Review of Physical Chemistry, 2007
- Resonance Surface Plasmon Spectroscopy: Low Molecular Weight Substrate Binding to Cytochrome P450Journal of the American Chemical Society, 2006
- Improving the Instrumental Resolution of Sensors Based on Localized Surface Plasmon ResonanceAnalytical Chemistry, 2006
- Plasmonic Properties of Film over Nanowell Surfaces Fabricated by Nanosphere LithographyThe Journal of Physical Chemistry B, 2005
- Single Silver Nanoparticles as Real-Time Optical Sensors with Zeptomole SensitivityNano Letters, 2003