Asparaginase Entrapped in Red Blood Cells: Action and Survival
- 20 August 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 193 (4254), 681-683
- https://doi.org/10.1126/science.821145
Abstract
As a strategy to avoid serious allergic reactions to the antitumor agent asparaginase, this enzyme was entrapped in autologous red blood cells before intravenous injection into monkeys. Additional advantages of this approach are prolonged enzyme half-life and targeting of this agent into the reticuloendothelial system.This publication has 11 references indexed in Scilit:
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