Hemodynamic Function at Rest, During Acute Stress, and in the Field
- 1 November 1999
- journal article
- other
- Published by Ovid Technologies (Wolters Kluwer Health) in Hypertension
- Vol. 34 (5), 1026-1031
- https://doi.org/10.1161/01.hyp.34.5.1026
Abstract
—Left ventricular hypertrophy is an independent predictor of cardiovascular morbidity and mortality. However, predictors of cardiac structure and function in youth are not completely understood. On 2 occasions (2.3 years apart), we examined 146 youth aged initially 10 to 19 years (mean age, 14.2±1.8 years). On the initial visit, hemodynamic function was assessed at rest, during laboratory stress (ie, orthostasis, car-driving simulation, video game, and forehead cold), and in the field (ie, ambulatory blood pressure). Quantitative M-mode echocardiograms were obtained on both visits. On both visits, black compared with white youth had higher resting laboratory systolic blood pressure ( P P 2.7 ( P P 2.7 were the initial evaluation of left ventricular mass/height 2.7 , body mass index, gender (males more than females), and supine resting total peripheral resistance (final model R 2 =0.53). Left ventricular mass/body surface area was predicted by initial left ventricular mass/body surface area, weight, gender, mean supine resting total peripheral resistance, and systolic pressure response to car-driving simulation (final model R 2 =0.48). Midwall fractional shortening was predicted by initial midwall fractional shortening, race (white more than black), and lower mean supine total peripheral resistance (final model R 2 =0.13). The clinical significance of these findings and their implications for improved prevention of cardiovascular diseases are yet to be determined.Keywords
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