A national survey of acute hepatitis E in France
Open Access
- 14 March 2008
- journal article
- Published by Wiley in Alimentary Pharmacology & Therapeutics
- Vol. 27 (11), 1086-1093
- https://doi.org/10.1111/j.1365-2036.2008.03679.x
Abstract
Background Few data are available on the incidence, risk factors and contamination pathways involved in acute indigenous hepatitis E in developed countries. Aims To draw up an overall picture of hepatitis E cases, to confirm whether or not the majority of the cases were indigenous and to attempt to identify the risk factors and contamination pathways involved in hepatitis E. Methods This study was performed in the framework of a national network (ANGH) including 96 participating centres. The 19 centres with at least one case of acute HEV reported a total number of 53 cases. Results A decreasing South‐to‐North geographic gradient was observed. A nonspecific clinical profile was observed in many cases. Acute hepatitis E was of indigenous origin in 90% of the patients. The most relevant and/or frequent possible risk factors among the 47 indigenous metropolitan cases were water consumption from a personal water supply, uncooked shellfish consumption and the recent acquisition of a pet pig. Conclusions This national survey confirmed that acute indigenous hepatitis E is an emerging disease in developed countries such as France, and suggests that various risk factors are responsible for acute indigenous hepatitis E contamination in non‐endemic countries.Keywords
This publication has 17 references indexed in Scilit:
- Possible Zoonotic Transmission of Hepatitis E from Pet Pig to Its OwnerEmerging Infectious Diseases, 2007
- Prevalence of Anti-Hepatitis E Virus Antibodies in French Blood DonorsJournal of Clinical Microbiology, 2007
- Fulminant liver failure from acute autochthonous hepatitis E in France: description of seven patients with acute hepatitis E and encephalopathyJournal of Viral Hepatitis, 2007
- Swine‐like hepatitis E viruses are a cause of unexplained hepatitis in the NetherlandsJournal of Viral Hepatitis, 2006
- Hepatitis E indigenous to economically developed countries: to what extent a zoonosis?Current Opinion in Infectious Diseases, 2006
- Autochthonous hepatitis E in southwest EnglandJournal of Viral Hepatitis, 2006
- Locally acquired hepatitis E virus infection, El Paso, TexasJournal of Medical Virology, 2006
- Hepatitis E in the south west of France in individuals who have never visited an endemic areaJournal of Medical Virology, 2004
- HEV identified in serum from humans with acute hepatitis and in sewage of animal origin in SpainJournal of Hepatology, 2000
- HEPATITIS E: An OverviewAnnual Review of Medicine, 1996