Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products

Abstract
BACKGROUND: Severe acute respiratory syndrome coronavirus (SARS‐CoV) has been detected in the blood of infected individuals, which may have the potential to contaminate donated blood and plasma‐derived products in the event of a future outbreak. Effective methods for inactivating the SARS‐CoV in protein solutions are described in this report.