Plasma anti-Müllerian hormone in adult dairy cows and associations with fertility
- 1 November 2014
- journal article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 97 (11), 6888-6900
- https://doi.org/10.3168/jds.2014-7908
Abstract
The objectives of this study were to identify factors associated with concentrations of anti-Müllerian hormone (AMH) in plasma of dairy cows and to investigate the relationships between plasma AMH and fertility responses during a 100-d breeding season. Lactating cows, 1,237 in 2 seasonally calving herds, had estrous cycles presynchronized and were enrolled in a timed artificial insemination (AI) protocol. All cows were inseminated on the first day of breeding season, considered study d 0. Blood was sampled on d -8 and analyzed for concentrations of AMH and progesterone. From d 19 to 35, detection of estrus was performed daily and cows detected in estrus were reinseminated. On d 36, bulls were placed with cows for 65 d of natural service breeding. Factors identified to be associated with concentrations of AMH in plasma were breed of the cow and lactation number. Concentrations of AMH were greater for Jerseys, followed by crossbreds, and then Holsteins. Cows on lactations 2 and 3 had greater concentrations of AMH than those on lactations 1 and ≥ 4. Although pregnancy per AI at the timed AI was not associated with concentrations of AMH, cows with low AMH had greater detection of estrus at timed AI, and the latter benefited pregnancy per AI, particularly in cows that had low progesterone at the beginning of the synchronization protocol. Pregnancy loss between gestation d 30 and 65 was greater in cows with low AMH compared with those with intermediate or high AMH. Return to estrus in cows that failed to become pregnant from the timed AI was not associated with AMH, but pregnancy rate in cows bred on estrus (reinsemination + natural service) was associated positively with AMH. In conclusion, breed and lactation number were identified to be associated with concentrations of AMH in plasma. Concentration of AMH was associated positively with maintenance of pregnancy at the first postpartum AI and with pregnancy rate in cows inseminated after detection of spontaneous estrus. Synchronization of ovulation might override positive associations between AMH and fertility.Keywords
This publication has 34 references indexed in Scilit:
- Targeted progesterone supplementation improves fertility in lactating dairy cows without a corpus luteum at the initiation of the timed artificial insemination protocolJournal of Dairy Science, 2013
- The Role of Anti-Müllerian Hormone (AMH) During Follicle Development in a Monovulatory Species (Sheep)Endocrinology, 2012
- Follicular wave of the ovulatory follicle and not cyclic status influences fertility of dairy cowsJournal of Dairy Science, 2010
- Evaluation of antral follicle count and ovarian morphology in crossbred beef cows: Investigation of influence of stage of the estrous cycle, age, and birth weight1,2Journal of Animal Science, 2009
- Period of dominance of the ovulatory follicle influences embryo quality in lactating dairy cowsReproduction, 2009
- Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathwaysReproductive Biology, 2008
- Numbers of Antral Follicles During Follicular Waves in Cattle: Evidence for High Variation Among Animals, Very High Repeatability in Individuals, and an Inverse Association with Serum Follicle-Stimulating Hormone Concentrations1Biology of Reproduction, 2005
- Regulation of ovarian function: the role of anti-Mullerian hormoneReproduction, 2002
- Endocrine and Neural Control of Estrus in Dairy CowsJournal of Dairy Science, 1994
- QUANTITATIVE MORPHOLOGICAL INVESTIGATIONS OF THE FOLLICULAR SYSTEM IN WOMENCells Tissues Organs, 1952