Ultrafast Intermolecular Zero Quantum Spectroscopy
- 19 November 2005
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (50), 17574-17575
- https://doi.org/10.1021/ja054463m
Abstract
Clinical magnetic resonance spectroscopy is typically limited by magnetic inhomogeneities which destroy spectral resolution, but intermolecular zero quantum coherences (iZQCs) are insensitive to such inhomogeneities. iZQC resolution in vivo, however, has been hampered by physiological fluctuations over the time scale of the two-dimensional acquisition. A faster iZQC sequence will allow us to average away these fluctuations, and thus we present a new approach to ultrafast two-dimensional spectroscopy. This communication reports iZQC experiments acquiring up to 31 t1-points per scan, as well as extensions to a broad range of other 2D sequences.Keywords
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