Sex influences on lung function and medication in childhood asthma

Abstract
Aim: To evaluate possible sex differences in prevalence, diagnosis and treatment of asthma, and influence on lung function associated with asthma severity in a population‐based birth cohort (BAMSE) of 4089 children. Methods: At 4‐y follow‐up, 92% responded to a questionnaire on symptoms of asthma, current medication and doctor's diagnosis of asthma. A total of 2965 children participated in clinical testing, including measurements of peak expiratory flow (PEF), and were assigned to groups of asthma or no asthma by reported airway symptoms. Results: Children in asthma groups had lower PEF readings compared to healthy children. This effect was most pronounced for both sexes in the persistent group (boys pConclusion: These results suggest that when 4‐y‐old children are stratified according to common diagnostic criteria, girls have a larger effect on PEF of asthma symptoms and are less frequently treated compared to boys.