The Seroprevalence of Hepatitis B and C in Hospitalized Danish Patients
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis Ltd in Scandinavian Journal of Infectious Diseases
- Vol. 27 (5), 445-448
- https://doi.org/10.3109/00365549509047043
Abstract
Health care workers are at risk of acquiring blood-borne infections. To assess the risk of exposure to hepatitis B or C in the case of occupational blood exposure, we determined the seroprevalence of these infections in 466 patients admitted to a Copenhagen university hospital. Serological markers for hepatitis B or C were detected in 56 patients (12.0%). The seroprevalence of HBsAg and anti-HCV was 0.9% and 1.5% respectively. HCV RNA, indicating ongoing hepatitis C, was found in five of seven anti-HCV-positive patients by polymerase chain reaction. The serological findings had not previously been diagnosed in 4 of 10 potentially infectious patients and only 6 of 10 patients belonged to high-risk groups. In conclusion, health care workers should be aware of the potential the occupational risk of hepatitis B and C even in a low-prevalence country like Denmark. Management of health care workers after blood exposure should include serological testing for both hepatitis B and C. Strict adherence to universal precautions is recommended and vaccination against hepatitis B should be encouraged.Keywords
This publication has 19 references indexed in Scilit:
- Transmission of Hepatitis C Virus Through Needlestick Accidents in Health Care WorkersPublished by Springer Science and Business Media LLC ,1994
- High Prevalence of Hepatitis C Virus (HCV) RNA in Dialysis Patients: Failure of Commercially Available Antibody Tests to Identify a Significant Number of Patients with HCV InfectionThe Journal of Infectious Diseases, 1993
- Hepatitis C virus antibodies in homosexual men and intravenous drug users in DenmarkInfection, 1993
- Hepatitis C virus infection in medical personnel after needlestick accidentHepatology, 1992
- Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis GenomeScience, 1989
- HEPATITIS B VIRUS INFECTION IN DANISH DENTISTSAmerican Journal of Epidemiology, 1988
- Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extractionAnalytical Biochemistry, 1987
- Hepatitis B Virus Infections among Danish SurgeonsThe Journal of Infectious Diseases, 1979
- Epidemiology of Hepatitis B Antigen and Antibody in Hospital Patients in CopenhagenScandinavian Journal of Infectious Diseases, 1975
- HEPATITIS-ASSOCIATED (AU/SH) ANTIGEN DETERMINATION IN 10,000 PATIENTS IN A COPENHAGEN GENERAL HOSPITALThe Lancet, 1970