More on Atypical Fractures of the Femoral Diaphysis

Abstract
Our experience has been very similar to that described by Lenart et al. (March 20 issue)1 in their report on atypical fractures of the femoral diaphysis. These fractures have a distinctive pattern and most likely represent completion of a stress fracture ( Figure 1 ). In our series,2 64.3% of the patients had involvement of the contralateral femur. In addition, 76% of the patients had documented prodromal symptoms of thigh pain, vague discomfort, or subjective weakness; these symptoms were often dismissed or treated as symptoms of spinal stenosis. “Giving way” of the involved limb immediately preceded the fall in 23.1% of the patients.3 We suggest that any patient receiving bisphosphonates who has thigh pain should undergo radiographic examination of the femur, and patients with a documented fracture should undergo radiographic examination of the contralateral femur. Prefracture diagnosis is challenging, as is defining the need for prophylactic fixation of a lateral cortical stress reaction that has been characterized by means of computed tomographic and magnetic resonance imaging (MRI) studies as a callus forming over an incomplete stress fracture.