Simultaneous Analysis of Four Diuretic Drugs by HPLC and Its Application to Health Food Supplements Advertising Weight Reduction.
Open Access
- 1 January 2002
- journal article
- abstracts
- Published by Japanese Society for Food Hygiene and Safety in Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
- Vol. 43 (2), 95-98
- https://doi.org/10.3358/shokueishi.43.95
Abstract
医薬品の添加が疑われる健康食品分析及び医薬品製剤の品質調査への応用を図る目的で，4種の汎用利尿薬のHPLCを用いた同時分析法について検討した．本法を利尿薬が配合された医薬品製剤の品質調査へ応用したところ，添加剤，賦形剤による妨害もなく，良好な定量結果が得られた．また，この方法を用いて痩身効果を標榜した健康食品中への利尿薬の添加の有無について確認したところ，試験した検体についてはいずれの利尿薬も検出されなかった．しかし，今後更に多くの検体について確認調査を実施していく必要があり，本法はそのスクリーニング法として有効と考えられる．This publication has 8 references indexed in Scilit:
- Furosemide assay in pharmaceuticals by Micellar liquid chromatography: study of the stability of the drugJournal of Pharmaceutical and Biomedical Analysis, 2000
- HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OFEPIRIZOLE AND TIARAMIDE INPHARMACEUTICAL PREPARATIONSJournal of Liquid Chromatography & Related Technologies, 2000
- Origin of Sennosides in Dietary Supplements Containing Senna Stem.Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 2000
- Determination of trichlormethiazide in bovine milk by high-performance liquid chromatographyJournal of Chromatography B: Biomedical Sciences and Applications, 1998
- Detection of Senna and Rhubarb Used Only as Drugs from Herbal Teas Advertising Effect of Weight Reduction.Eisei kagaku, 1998
- Components of Herbal Ecstacies.Eisei kagaku, 1997
- Simultaneous determination of spironolactone and its metabolites in human plasmaJournal of Pharmaceutical and Biomedical Analysis, 1996
- Determination of ephedrine compounds in nutritional supplements by cyclodextrin-modified capillary electrophoresisJournal of Chromatography B: Biomedical Sciences and Applications, 1995