Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage
- 14 April 2010
- journal article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 25 (6), 1543-1552
- https://doi.org/10.1093/humrep/deq091
Abstract
BACKGROUND The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.Keywords
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