Zinc and Molybdenum Co-Doped BiVO4 Nanoarray for Photoelectrochemical Diethylstilbestrol Analysis Based on the Dual-Competitive System of Manganese Hexacyanoferrate Hydrate Nanocubes
- 8 April 2020
- journal article
- research article
- Published by American Chemical Society (ACS) in ACS Applied Materials & Interfaces
- Vol. 12 (14), 16662-16669
- https://doi.org/10.1021/acsami.0c04010
Abstract
This study proposes a competitive photoelectrochemical (PEC) immunosensor for detecting diethylstilbestrol (DES). The PEC sensing platform uses a zinc and molybdenum codoped BiVO4 nanoarray ((Zn,Mo):BiVO4) as the photoactive matrix and manganese hexacyanoferrate hydrate loading silicon dioxide layer composite nanocubes (MHCF@SiO2 NCs) as the signal quencher. The (Zn,Mo):BiVO4 nanoarray demonstrated brilliant PEC behavior, by virtue of the local electric field formed by the codoped Zn and Mo. This doping accelerated the electron transfer and improved the photoelectric conversion efficiency in BiVO4 nanoarray under visible light. Furthermore, the nanoarray structure with its large surface area provided abundant binding sites for the immune response. As the MHCF@SiO2 NCs-anti-DES competitively bonded with either free DES or bovine serum albumin conjugated DES (BSA-DES), hydrogen peroxide (H2O2) as electron donor was competitively consumed and meanwhile steric resistance blocked electrons transfer. For the above reasons, the photocurrent signal was reduced. Thus, the standard sample free DES was accurately detected, and the fabricated PEC immunosensor displayed an outstanding photocurrent response from 0.1 pg/mL to 50 ng/mL with a detection limit of 0.05 pg/mL. Simultaneously, the acceptable stability, selectivity, and reproducibility of the designed dual-competitive sensing platform suggest its applicability to small molecule detection.Funding Information
- National Natural Science Foundation of China (21505051, 21575050, 21675063, 21777056)
- Jinan Scientific Research Leader Workshop Project (2018GXRC024)
This publication has 39 references indexed in Scilit:
- Novel Mn3[Co(CN)6]2@SiO2@Ag Core–Shell Nanocube: Enhanced Two‐Photon Fluorescence and Magnetic Resonance Dual‐Modal Imaging‐Guided Photothermal and Chemo‐therapySmall, 2015
- Uniform manganese hexacyanoferrate hydrate nanocubes featuring superior performance for low-cost supercapacitors and nonenzymatic electrochemical sensorsNanoscale, 2015
- Mo‐Doped BiVO4 Photoanodes Synthesized by Reactive SputteringChemSusChem, 2015
- Nanostructured bismuth vanadate-based materials for solar-energy-driven water oxidation: a review on recent progressNanoscale, 2014
- Photoelectrochemical bioanalysis: the state of the artChemical Society Reviews, 2014
- Nanoporous BiVO 4 Photoanodes with Dual-Layer Oxygen Evolution Catalysts for Solar Water SplittingScience, 2014
- Simultaneously Efficient Light Absorption and Charge Separation in WO3/BiVO4 Core/Shell Nanowire Photoanode for Photoelectrochemical Water OxidationNano Letters, 2014
- Recent advances in semiconductors for photocatalytic and photoelectrochemical water splittingChemical Society Reviews, 2014
- Marked enhancement in electron–hole separation achieved in the low bias region using electrochemically prepared Mo-doped BiVO4photoanodesPhysical Chemistry Chemical Physics, 2013
- Emerging molecular biomarkers—blood-based strategies to detect and monitor cancerNature Reviews Clinical Oncology, 2011