Sulfadiazine-induced nephrolithiasis in children
- 17 June 2004
- journal article
- case report
- Published by Springer Science and Business Media LLC in Pediatric Nephrology
- Vol. 19 (8), 928-931
- https://doi.org/10.1007/s00467-004-1519-8
Abstract
Sulfadiazine-associated urinary calculi have been described in HIV-positive adult patients but rarely in children. We report two pediatric cases of sulfadiazine-induced nephrolithiasis and review 45 adult cases from the literature. One had a hyper-IgM syndrome and was treated with sulfadiazine for cerebral toxoplasmosis, the other had toxoplasmic retinitis. Both developed multiple bilateral lithiasis with acute renal failure. Normalization of renal function and reduction of calculi size was rapidly achieved after discontinuation of sulfadiazine, hyperhydration, and alkalinization. Bilateral ureteral stents were required in one patient because of anuria.Keywords
This publication has 27 references indexed in Scilit:
- Obstructive nephropathy due to sulfa crystals in two HIV seropositive patients treated with sulfadiazine.1999
- Sulfadiazine-Associated Nephrotoxicity in Patients with the Acquired Immunodeficiency SyndromeMedicine, 1996
- Reversible acute renal failure due to sulfonamide-induced lithiasis in an AIDS patient.1995
- [Sulfadiazine nephrolithiasis and nephropathy].1994
- Renal alterations induced by sulfadiazine therapy in an AIDS patients.1994
- Acute renal failure and sulphadiazine crystalluria in kidney transplantNephrology Dialysis Transplantation, 1994
- Renal failure due to sulphadiazine in AIDS patients with cerebral toxoplasmosisJournal of Internal Medicine, 1993
- [Acute renal failure caused by sulfadiazine crystalluria in AIDS. An historical resurgent iatrogenic complication].1992
- Obstructive Renal Failure due to Therapy with Sulfadiazine in an AIDS PatientNephron, 1992
- Anuria due to sulphadiazine.Archives of Disease in Childhood, 1973