Topiramate-induced angle closure with acute myopia, macular straie
Open Access
- 1 January 2010
- journal article
- case report
- Published by Medknow in Oman Journal of Ophthalmology
- Vol. 3 (1), 26-28
- https://doi.org/10.4103/0974-620x.60018
Abstract
Topiramate is a sulfamate-substituted monosaccharide used in the treatment of seizures, and prophylaxis of migraine. A number of ocular side-effects have been described with use of topiramate, like bilateral angle closure, acute myopia and macular striae. Ultrasound biomicroscopy (UBM) clinches the diagnosis after ruling out other causes of shallow anterior chamber. Previous studies have not demonstrated internal limiting membrane folds presenting as macular striae. We report a case of topiramate-induced acute myopia with angle closure and macular striae in a young adult. This is the first report wherein striae formation after low doses of topiramate and their resolution have been documented by Optical Coherence Tomography (OCT).Keywords
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