3D nanostructural analysis of silk fibroin and recombinant spidroin 1 scaffolds by scanning probe nanotomography
- 10 November 2014
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 4 (105), 60943-60947
- https://doi.org/10.1039/c4ra08341e
Abstract
We use serial section scanning probe nanotomography to study the 3D structure, nanoporosity and pore interconnectivity of biocompatible scaffolds made of fibroin and recombinant spidroin 1 (rS1/9). Significant nanoporosity (24%) and pore percolation is detected for rS1/9 scaffolds. It is assumed to contribute to higher in vivo tissue regeneration efficiency of rS1/9 scaffolds.Keywords
This publication has 39 references indexed in Scilit:
- Tissue regeneration in vivo within recombinant spidroin 1 scaffoldsBiomaterials, 2012
- Local Organization of Graphene Network Inside Graphene/Polymer CompositesAdvanced Functional Materials, 2012
- In vitro and in vivo biocompatibility studies of a recombinant analogue of spidroin 1 scaffoldsJournal of Biomedical Materials Research Part A, 2010
- The formation of a quaternary structure by recombinant analogs of spider silk proteinsMolecular Biology, 2010
- Development of biomaterial scaffold for nerve tissue engineering: Biomaterial mediated neural regenerationJournal of Biomedical Science, 2009
- Three-dimensional Electrical Property Mapping with Nanometer ResolutionAdvanced Materials, 2009
- Silk-inspired polymers and proteinsBiochemical Society Transactions, 2009
- Manufacture of degradable polymeric scaffolds for bone regenerationBiomedical Materials, 2008
- Spider silks and their applicationsTrends in Biotechnology, 2008
- Silk-based biomaterialsBiomaterials, 2003