Nanomaterials in the Environment: From Materials to High-Throughput Screening to Organisms
- 25 January 2011
- journal article
- review article
- Published by American Chemical Society (ACS) in ACS Nano
- Vol. 5 (1), 13-20
- https://doi.org/10.1021/nn1034857
Abstract
One of the challenges in the field of nanotechnology is environmental health and safety (EHS), including consideration of the properties of engineered nanomaterials (ENMs) that could pose dangers to the environment. Progress in the field of nanomaterial development and nanotoxicology was presented at the International Conference on the Environmental Implications of Nanotechnology at the California NanoSystems Institute (CNSI) on the UCLA campus on May 11-14, 2010. This event was cohosted by the University of California Center for the Environmental Implications of Nanotechnology (UC CEIN) and the Center for the Environmental Implications of NanoTechnology (CEINT) based at Duke University. Participants included scientists and scholars from various backgrounds, including chemistry, biology, engineering, nanomaterial science, toxicology, ecology, mathematics, sociology, and policy makers. The topics of discussion included safety evaluation of ENMs from an environmental perspective, nanotoxicology, ecotoxicology, safe design of ENMs, environmental risk assessment, public perception of nanotechnology, application of ENMs in consumer products, and many more. The UC CEIN presented data on their predictive toxicological approach to the assessment of ENM libraries, which were designed and synthesized to develop an understanding of the material properties that could lead to hazard generation at the cellular and organismal levels in the environment. This article will focus on the first metal oxide ENM library that was introduced to harmonize research activities in the UC CEIN, with particular emphasis on the safety assessment of ZnO on cells and organisms. Methods of decreasing the observed toxic effects will also be discussed as an integral component of the UC CEIN's activity in developing safer nanomaterials to lessen their environmental impacts.This publication has 30 references indexed in Scilit:
- Dispersion of TiO 2 Nanoparticle Agglomerates by Pseudomonas aeruginosaApplied and Environmental Microbiology, 2010
- Dispersion and Stability Optimization of TiO2 Nanoparticles in Cell Culture MediaEnvironmental Science & Technology, 2010
- Stability and Aggregation of Metal Oxide Nanoparticles in Natural Aqueous MatricesEnvironmental Science & Technology, 2010
- Use of a Rapid Cytotoxicity Screening Approach To Engineer a Safer Zinc Oxide Nanoparticle through Iron DopingACS Nano, 2009
- A Predictive Toxicological Paradigm for the Safety Assessment of NanomaterialsACS Nano, 2009
- Optimized dispersion of nanoparticles for biological in vitro and in vivo studiesParticle and Fibre Toxicology, 2008
- A biocompatible medium for nanoparticle dispersionNanotoxicology, 2008
- Improved method to disperse nanoparticles forin vitroandin vivoinvestigation of toxicityNanotoxicology, 2007
- Toxic Potential of Materials at the NanolevelScience, 2006
- Adsorption of bacterial surface polysaccharides on mineral oxides is mediated by hydrogen bondsColloids and Surfaces B: Biointerfaces, 1997