Set-related neuronal activity in the premotor cortex of rhesus monkeys: effects of changes in motor set

Abstract
The work on the mechanism of reduction of steroid 7(8) 14(15) and 24(25) double bonds is summarized. On the basis of the results obtained it is suggested that the first crucial event in the pyridine nucleotide-linked reduction is the activation of the substrate through protonation to give an electron deficient species which in the next step is neutralized by the addition of a hydride from NAD(P)H to furnish the product.