Myosin V motor proteins
Open Access
- 10 November 2003
- journal article
- review article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 163 (3), 445-450
- https://doi.org/10.1083/jcb.200308093
Abstract
Mammalian myosin V motors transport cargo processively along actin filaments. Recent biophysical and structural studies have led to a detailed understanding of the mechanism of myosin V, making it perhaps the best understood cytoskeletal motor. In addition to describing the mechanism, this review will illustrate how “dynamic” single molecule measurements can synergize with “static” protein structural studies to produce amazingly clear information on the workings of a nanometer-scale machine.Keywords
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