Cognitive function and quality of life after surgery for early breast cancer in North Jutland, Denmark
Open Access
- 1 January 2009
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Oncologica
- Vol. 48 (4), 532-540
- https://doi.org/10.1080/02841860802600755
Abstract
Objective. The aim of this study was to assess cognitive function, quality of life, and psychological distress after surgery for early breast cancer but before initiation of adjuvant treatment. Material and methods. We performed a population-based study in the county of North Jutland, Denmark, including 124 women aged less than 60 years who had surgery for early breast cancer from 2004 – 2006. They were compared with an aged-matched group of 224 women without previous cancer selected randomly from the same population. The cognitive function of patients and controls was tested using a revised battery from the ISPOCD study. Data were collected on quality of life (EORTC QLQ-C30) and psychological distress (POMS). Result. The neuropsychological tests did not reveal significant differences between patients and controls. Compared to the control group, breast cancer patients had a significantly 3 – 4 fold increased risk of experiencing cognitive impairment. Quality of life and psychological distress were also significantly poorer among patients. Conclusion. This study demonstrated that women diagnosed with breast cancer experience a significant deterioration of their perceived cognitive functioning, quality of life and of psychological well being.Keywords
This publication has 19 references indexed in Scilit:
- Cognitive function during neoadjuvant chemotherapy for breast cancerCancer, 2007
- Cognitive impairment associated with adjuvant therapy in breast cancerPsycho‐Oncology, 2005
- General self‐efficacy in various domains of human functioning: Evidence from five countriesInternational Journal of Psychology, 2005
- ‘Chemobrain’ in breast carcinoma?Cancer, 2004
- Pre‐treatment factors related to cognitive functioning in women newly diagnosed with breast cancerPsycho‐Oncology, 2004
- Postoperative Cognitive Dysfunction in Middle-aged PatientsAnesthesiology, 2002
- Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 studyThe Lancet, 1998
- Neuropsychological assessment of cognitive functioning following chemotherapy for breast cancerPsycho‐Oncology, 1995
- The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in OncologyJNCI Journal of the National Cancer Institute, 1993
- Dementia: The Estimation of Premorbid Intelligence Levels Using the New Adult Reading TestCortex, 1978