Engineering precision biomaterials for personalized medicine
- 17 January 2018
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 10 (424)
- https://doi.org/10.1126/scitranslmed.aam8645
Abstract
As the demand for precision medicine continues to rise, the “one-size-fits-all” approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.Keywords
Funding Information
- National Institutes of Health (award299535, 1F32HL137256-01)
- National Institutes of Health (award299536, RHL132353A)
- National Institutes of Health (award335848, 5F32HL121986-02)
- National Institutes of Health (award335849, 5R21AR067469-02)
- Howard Hughes Medical Institute (award299752)
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