Engineering precision biomaterials for personalized medicine

Abstract
As the demand for precision medicine continues to rise, the “one-size-fits-all” approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.
Funding Information
  • National Institutes of Health (award299535, 1F32HL137256-01)
  • National Institutes of Health (award299536, RHL132353A)
  • National Institutes of Health (award335848, 5F32HL121986-02)
  • National Institutes of Health (award335849, 5R21AR067469-02)
  • Howard Hughes Medical Institute (award299752)