Identification of a new prostate cancer susceptibility locus on chromosome 8q24
- 20 September 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Genetics
- Vol. 41 (10), 1055-1057
- https://doi.org/10.1038/ng.444
Abstract
We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We identify a new association with prostate cancer risk on chromosome 8q24 (rs620861, P = 1.3 x 10(-10), heterozygote OR = 1.17, 95% CI 1.10-1.24; homozygote OR = 1.33, 95% CI 1.21-1.45). This defines a new locus associated with prostate cancer susceptibility on 8q24.Keywords
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