PIK3CA Mutation Associates with Improved Outcome in Breast Cancer
Open Access
- 12 August 2009
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 15 (16), 5049-5059
- https://doi.org/10.1158/1078-0432.ccr-09-0632
Abstract
Purpose: In breast cancer, somatic mutations in the PIK3CA gene are common. The prognostic implication of these activating mutations remains uncertain as moderately sized studies have yielded variable outcomes. Our aim was to determine the prognostic implications of PIK3CA mutations in breast cancer.Keywords
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