Risk of Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis in Patients With Acute Ischemic Stroke and High Cerebral Microbleed Burden

Abstract

Cerebral microbleeds (CMBs) as visualized on gradient echo T2* or susceptibility-weighted magnetic resonance imaging (MRI) are considered markers of bleeding-prone cerebral vessel microangiopathies and constitute both significant and independent predictors of future cerebral bleeding.^1-3 Several clinical studies have associated CMB presence with hemorrhagic stroke and hemorrhagic complications following antithrombotic medications.⁴