Migrasomes: a new organelle of migrating cells
- 7 November 2014
- journal article
- comment
- Published by Springer Science and Business Media LLC in Cell Research
- Vol. 25 (1), 1-2
- https://doi.org/10.1038/cr.2014.146
Abstract
Cell migration is a multi-step process that involves the coordinated action of signaling networks, cytoskeletal dynamics and vesicular trafficking, leading to protrusion and adhesion at the leading edge of cells and contraction and detachment at their rear. In a recent paper in Cell Research, Ma et al. describe the biogenesis of a new exosome-like organelle--named migrasomes--that derive from retraction fibers at the rear of migrating cells and their potential roles in inter-cellular signaling.Keywords
This publication has 14 references indexed in Scilit:
- Substrate-attached materials are enriched with tetraspanins and are analogous to the structures associated with rear-end retraction in migrating cellsCell Adhesion & Migration, 2013
- SHARPIN is an endogenous inhibitor of β1-integrin activationNature, 2011
- Plasticity of cell migration: a multiscale tuning modelThe Journal of cell biology, 2009
- Trafficking and Cell MigrationTraffic, 2009
- Release of cell fragments by invading melanoma cellsEuropean Journal of Cell Biology, 2004
- Exosomes: endosomal-derived vesicles shipping extracellular messagesCurrent Opinion in Cell Biology, 2004
- Mechanism of Blebbistatin Inhibition of Myosin IIJournal of Biological Chemistry, 2004
- Cell Migration: Integrating Signals from Front to BackScience, 2003
- Adhesion assembly, disassembly and turnover in migrating cells – over and over and over againNature, 2002
- Cell Migration: A Physically Integrated Molecular ProcessCell, 1996