A retrospective clinico‐pathological study comparing lichen planus pigmentosus with ashy dermatosis
- 10 April 2018
- journal article
- research article
- Published by Wiley in Australasian Journal of Dermatology
- Vol. 59 (4), 322-327
- https://doi.org/10.1111/ajd.12813
Abstract
Background/Objectives Controversy persists as to whether lichen planus pigmentosus and ashy dermatosis are separate clinical entities. This study was conducted to examine the clinicopathological features and treatment outcome of the two conditions. Methods A retrospective medical chart review of all patients who were diagnosed with lichen planus pigmentosus or ashy dermatosis was conducted. The information collected included the participants’ age at onset, site of onset, duration of disease, presence of precipitating factors, distribution of disease, pigmentation and presence of symptoms. In patients from whom a biopsy was taken the histopathological reports were included. Results Altogether 26 patients with ashy dermatosis and 29 with lichen planus pigmentosus were included in the study. Compared with ashy dermatosis, lichen planus pigmentosus had a more localised distribution with a preponderance for facial involvement, compared with the truncal preponderance in ashy dermatosis. Ashy dermatosis tended to have a more stable clinical course than lichen planus pigmentosus, which was more likely to wax and wane. The utility of histopathology in differentiating between the two conditions is low. Conclusion Ashy dermatosis and lichen planus pigmentosus, as defined in this study, appear to be two separate clinical entities with distinguishable clinical features and natural histories.Keywords
This publication has 13 references indexed in Scilit:
- Low‐dose oral isotretinoin therapy in lichen planus pigmentosus: an open‐label non‐randomized prospective pilot studyInternational Journal of Dermatology, 2016
- Macular pigmentation of uncertain aetiology revisited: two case reports and a proposed algorithm for clinical classificationAustralasian Journal of Dermatology, 2016
- Lichen planus pigmentosus: a retrospective clinico‐epidemiologic study with emphasis on the rare follicular variantJournal of the European Academy of Dermatology and Venereology, 2015
- A case of lichen planus pigmentosus that was recalcitrant to topical treatment responding to pigment laser treatmentDermatologic Therapy, 2014
- Linear lichen planus pigmentosus of the forehead treated by neodymium:yttrium-aluminum-garnet laser and topical tacrolimusThe Journal of Dermatology, 2011
- Clinicopathological characteristics of lichen planus pigmentosus and its response to tacrolimus ointment: an open label, non‐randomized, prospective studyJournal of the European Academy of Dermatology and Venereology, 2010
- Erythema dyschromicum perstans in children: a report of 14 casesJournal of the European Academy of Dermatology and Venereology, 2005
- ASHY DERMATOSIS VERSUS LICHEN PLANUS PIGMENTOSUS: A CONTROVERSIAL MATTERInternational Journal of Dermatology, 1992
- ASHY DERMATOSIS AND LICHEN PLANUS PIGMENTOSUS: A CLINICOPATHOLOGIC STUDY OF 31 CASESInternational Journal of Dermatology, 1992
- Lichen planus pigmentosusDermatology, 1974